#Mira safety trial#

'We are very pleased with the compelling safety results in young children from the MIRA-4 trial, marking the fourth positive data milestone in our Nyxol program in RM,' said Mina Sooch, MBA, Founder and CEO of Ocuphire Pharma. The company is currently evaluating partnering and distribution options for an effective and cost-efficient commercial launch of Nyxol targeted for the second half of 2023, if approved. Ocuphire plans to submit an NDA that includes the results of MIRA-1, MIRA-2, MIRA-3, and MIRA-4 with the U.S. MIRA-4 enrolled 23 pediatric subjects from two sites in the U.S in two months. MIRA-4 is part of the comprehensive MIRA clinical program to develop Nyxol for RM. Nyxol is a proprietary, preservative-free, stable, investigational eye drop formulation of phentolamine mesylate designed to uniquely modulate the pupil size by blocking the α1 receptors found only on the iris dilator muscle without affecting the ciliary muscle. The results demonstrated that Nyxol's efficacy and safety in pediatric subjects 3-11 years of age was consistent with that shown in previous studies conducted by Ocuphire which enrolled both adolescents (age 12-17 years) and adults (age 18 years and older), showing a rapid reversal of pharmacologically-induced mydriasis (RM) and a favorable safety profile.

#Mira safety trial#

OCUP, a clinical-stage ophthalmic biopharmaceutical company focused on developing and commercializing therapies for the treatment of refractive and retinal eye disorders, today announced positive results in the MIRA-4 pediatric safety trial investigating its product candidate Nyxol ® for the reversal of pharmacologically-induced mydriasis (dilation of pupil). The vision is deep and with no obstacles or dead angles, and there is a nice cooling system in place.NDA Filing for Nyxol in RM Planned for Late 2022 with Potential Launch in 2H 2023įARMINGTON HILLS, Mich., Ap(GLOBE NEWSWIRE) - Ocuphire Pharma, Inc. The design comes in 3 sizes and is perfect for all on-field operatives or preppers that need protection from gasses. This hydration system will allow a fluid intake of 230 ml per minute.Īll in all, the MIRA Safety CM-7M military gas mask is durable and made of quality materials. Also, this mask has a built-in drinking canteen which not many masks include. You can regulate the temperature through an innovative exhalation chamber with a sweat drainage system. MIRA mask resists up to 20 pascals which makes it the most breathable military-grade mask available.Īdditionally, the CM-7M mask has two mechanisms to prevent the air in the mask from getting too hot. It is a perfect mask for the field of battle with the presence of toxic gases.

Under proper storage conditions, this mask will last at least 20 years without any deterioration.Īlso, breathing resistance is low. The first thing to mention is that the MIRA Safety CM-7M mask has a long shelf life.

What’s more, the lenses on this mask are treated with a super helpful anti-fog solution. This allows for a wide peripheral range and this design can improve depth perception and combat performance, which as a result makes the MIRA safety mask a great combat gas mask, as well. That is why this police gas mask model has a dual-lens vision window instead of a visor. The biggest benefit of the design of the MIRA Safety US military gas mask is that it can accommodate all riflemen who need lenses in order to perform their duties.

To some, the exhalation valve position may be awkward.

The spectacle kit is not included with the mask.

Lightweight and highly comfortable, can wear for many hoursĮven though this is a great quality army gas mask, it could improve in some areas.

Resistance to CBRN agents, industrial toxic gases and riot control gases.

Compatible with CamelBak water bladders.

This mask is compatible with different types of optical devices such as night vision googles.

However, These military-grade gas masks hold plenty of benefits and are affordable to the common Joe. Also, the personal protective equipment or PPE industry has plenty of upgrades all the time, and sometimes existing products may have some room for improvement in some of their areas. MIRA Safety CM-7M mask is a comprehensive mask that has plenty of benefits. That is why we present you with the MIRA Safety CM 7M military gas mask review. Today, there are plenty of different military gas masks out there and it is hard to be sure which ones are good. A quality military-grade face mask needs to be sturdy, and durable, and not compromise its integrity or functionality. Most military special unit forces, a member of a rescue team or anyone preparing for SHTF scenarios will be needing a reliable and comfortable gas mask.